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Liver Referral Criteria

Reasons for Liver Transplant
A patient should be considered for liver transplant if the following conditions are present:

  • Irreversible liver disease with no effective medical or surgical alternatives to transplantation
  • Chronic liver disease that interferes with the patient’s ability to work or sustain meaningful quality of life
  • Predictable mortality from liver disease exceeding transplantation prognosis (85% one-year survival, 70% five-year survival)
  • Cholestatic Disease: primary biliary cirrhosis, sclerosing cholangitis, secondary biliary cirrhosis, biliary atresia, cystic fibrosis
  • Chronic Hepatitis: hepatitis B, hepatitis C, hepatitis D, autoimmune chronic active hepatitis, cryptogenic cirrhosis, chronic drug toxicity or toxin exposure
  • Alcoholic Cirrhosis: Patients with alcoholic cirrhosis are considered for transplant if they can achieve abstinence and rehabilitation.
  • Metabolic Diseases: hemochromatosis, Wilson's disease, Alpha-1-antitrypsin deficiency, glycogen storage disease, tyrosinemia, familial amyloidotic polyneuropathy, other metabolic disorders treatable by liver replacement
  • Fulminant Acute Hepatic Necrosis: viral hepatitis, drug toxicity
  • Primary Hepatic Tumors: selected patients with hepatocellular carcinoma

Transplant Eligibility Considerations
Patients are considered eligible for transplant if the following conditions are met:

  • End-stage liver disease
  • Absence of systemic illness or other medical conditions relevant to survival
  • Full comprehension of transplant procedures and issues

If patients do not meet these criteria at the time of referral, they may return for re-evaluation at a later date. Psychiatric assessment is required for patients who fail to meet alcohol or drug abstinence requirements in their initial evaluation.

Contraindications for Liver Transplant
Patients are not considered transplant candidates if any of the following conditions exist:

  • Active drug or alcohol use
  • Patient history indicating other end-stage medical conditions
  • Metastatic cancer

To expedite patient evaluation, please include the following information with any referral to University Transplant Center:

  • Name of the primary attending physician for patient
  • Office address, fax, referring physician e-mail and telephone numbers
  • Recent patient record, physicals and history
  • All lab results within previous 3 months
  • Liver biopsy slides
  • Recent abdominal imaging/scans/EGD
  • Patient insurance information, including copy of card

Fill out the referral form

 
Liver